AOD-9604 dosage for fat loss in Canada typically ranges from 250 mcg to 500 mcg per day, split into one or two subcutaneous injections. Most users start at 250 mcg daily and may increase to 500 mcg after assessing tolerance. This peptide is not approved by Health Canada for human use, so all dosing guidance comes from clinical research and anecdotal reports.
AOD-9604 is a modified fragment of human growth hormone (hGH), specifically amino acids 177-191. It was designed to retain the fat-burning properties of hGH without affecting blood sugar or cell proliferation. In Canada, AOD-9604 is sold as a research chemical, and many people buy it online for personal fat loss experiments. The question of how much to take is common, but there is no official dosing standard.
What Is AOD-9604 and How Does It Work?
AOD-9604 mimics the lipolytic region of growth hormone. It stimulates lipolysis, the breakdown of fat, and inhibits lipogenesis, the creation of new fat. Unlike full hGH, it does not raise IGF-1 levels significantly, which reduces the risk of insulin resistance. This makes it attractive for fat loss without the side effects of hGH.
Clinical trials in the early 2000s tested AOD-9604 for obesity. Doses ranged from 1 mg to 30 mg per day in those studies, but those were oral formulations. The injectable form used by researchers today is much lower, typically 250 mcg to 500 mcg daily. This is because subcutaneous injection delivers the peptide directly into the bloodstream, bypassing digestive breakdown.
AOD-9604 Dosage for Fat Loss: The Standard Protocol
The most common AOD-9604 dosage for fat loss is 250 mcg to 500 mcg per day. Some protocols split this into two doses: 250 mcg in the morning and 250 mcg in the evening. Others use a single 300 mcg injection before fasted cardio. There is no consensus, but the range is consistent across peptide forums and vendor recommendations.
Here is a typical cycle for a beginner in Canada:
- Weeks 1-2: 250 mcg once daily, preferably in the morning or before exercise.
- Weeks 3-8: 250 mcg twice daily (total 500 mcg), with the second dose in the late afternoon.
- Cycle length: 8 to 12 weeks, followed by a 4-week break.
Some users report better results with 500 mcg once daily, but splitting the dose may maintain steadier peptide levels. AOD-9604 has a short half-life, estimated at under 30 minutes, so frequent dosing could theoretically improve fat oxidation. However, no human study has compared once-daily versus twice-daily dosing for fat loss.
How to Reconstitute and Inject AOD-9604
AOD-9604 is sold as a lyophilized powder in vials, usually 2 mg or 5 mg. To reconstitute, add bacteriostatic water. For a 2 mg vial, adding 2 mL of water gives a concentration of 1000 mcg per mL. Then 0.25 mL equals 250 mcg. Use an insulin syringe for subcutaneous injection into the abdomen or thigh.
Storage matters. Keep the powder refrigerated before reconstitution. After mixing, store the vial in the fridge and use within 30 days. Do not shake the vial; swirl gently. If the solution becomes cloudy, discard it. In Canada, you can buy AOD-9604 from online peptide suppliers, but quality varies. Always request a certificate of analysis.
AOD-9604 Canada: Legal Status and Buying Considerations
In Canada, AOD-9604 is not approved by Health Canada for any therapeutic use. It is not a controlled substance, so possession is not illegal, but selling it for human consumption is prohibited. Most Canadian vendors label it "for research purposes only" or "not for human use." This is a legal gray area, but many people still buy it for personal fat loss.
When buying AOD-9604 in Canada, look for third-party testing. Reputable vendors post lab results showing purity above 98%. Prices vary: a 2 mg vial typically costs $30 to $50 CAD, while a 5 mg vial runs $60 to $90 CAD. Buying in bulk reduces the per-mg cost. Some Canadian peptide shops offer discounts for orders over $200.
If you are new to peptides, you might also be interested in BPC-157 pricing in Quebec for healing support. But for fat loss, AOD-9604 is a more targeted choice.
AOD-9604 vs Other Fat Loss Peptides
AOD-9604 is often compared to HGH Fragment 176-191, which is essentially the same peptide. In fact, AOD-9604 is a modified version of Fragment 176-191 with an added tyrosine to improve stability. The dosing is similar, but AOD-9604 is considered more stable in solution. Other fat loss peptides include Tesamorelin, which is approved for HIV-related lipodystrophy, and CJC-1295 with Ipamorelin, which boosts natural GH release.
For pure fat loss without muscle gain, AOD-9604 is a popular choice because it does not increase hunger or affect blood sugar. Semaglutide and Tirzepatide are also used for weight loss, but they work through appetite suppression and glucose control, not direct lipolysis. AOD-9604 is more of a fat burner than an appetite suppressant.
Expected Results and Timeline
Most users report noticeable fat loss after 4 to 6 weeks of consistent dosing. AOD-9604 is not a miracle drug; it works best with a caloric deficit and regular exercise. Some people combine it with fasted cardio in the morning to enhance lipolysis. Results are gradual, often 1 to 2 pounds of fat loss per week when diet is on point.
Before and after photos from peptide users show modest reductions in abdominal fat over 8 to 12 weeks. The peptide seems to target stubborn fat areas, but this is anecdotal. Clinical trials showed mixed results, with some studies finding no significant weight loss compared to placebo. However, those trials used oral AOD-9604, not injectable, and the doses were much higher.
Side Effects and Safety
AOD-9604 is generally well tolerated. Reported side effects include mild injection site reactions, headache, and nausea. Because it does not raise IGF-1, it does not cause the joint pain or insulin resistance seen with hGH. Long-term safety data is lacking, so cycles should be limited to 12 weeks with breaks.
Do not use AOD-9604 if you are pregnant, nursing, or have a history of cancer. Growth hormone fragments can theoretically stimulate cell growth, though AOD-9604 was designed to avoid this. Always consult a healthcare provider before starting any peptide, especially if you have a medical condition or take medications.
Where to Buy AOD-9604 in Canada
You can buy AOD-9604 online from Canadian peptide suppliers. Look for vendors that ship from within Canada to avoid customs delays. Payment is usually by e-transfer or credit card. Some popular Canadian peptide shops include CanLab, Peptide Sciences Canada, and BioPeptide. Always check reviews and lab testing before ordering.
For those in Quebec, the process is the same, but French-language customer service may be a plus. If you are also interested in healing peptides, check out this comparison of BPC-157 vs TB-500 for healing. But for fat loss, AOD-9604 remains a top choice.
Final Dosage Recommendations
Start with 250 mcg of AOD-9604 once daily for the first week. If tolerated, increase to 250 mcg twice daily for a total of 500 mcg per day. Run this for 8 to 12 weeks, then take a 4-week break. Combine with a calorie deficit and regular exercise for best results. In Canada, AOD-9604 is easy to source online, but always verify purity and storage conditions.
Remember that AOD-9604 is a research chemical, not a proven weight loss drug. The dosage range of 250 to 500 mcg per day is based on anecdotal reports and extrapolation from animal studies. Your results may vary. If you are looking for a more established fat loss option, consider discussing Semaglutide or Tirzepatide with a doctor. But for a direct lipolytic peptide, AOD-9604 at 250 to 500 mcg daily is the standard starting point.